Forced degradation robot
Labman has supplied two Forced Degradation Robots to Pfizer, one at the Sandwich site in the UK and the latest one in La Jolla, San Diego. The later robot was installed in 2001 and was used for preparing samples of candidate drug powders prior to stress testing and analysis. Over a period of 3 years the robot had various upgrades to further enhance the functionality and increase the level of automation for the degradation process.
Sample Purification robot
The sample purification robot was installed at Medimmune, Cambridge in 2007 and was designed to replace an existing system that required a lot of user intervention during the purification process. The robot is used as part of the development of human monoclonal antibody therapeutics and performs the initial sample purification by passing a number of reagents through SPE columns followed by the sample. The resultant purified sample is collected in Eppendorf tubes ready for aliquoting. The final samples are aliquoted into Micronics tubes, microtitre plates and PCR well plates. The robot runs 3 batches of 48 samples over a 24 hour period.